SAFB2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70616
Background:
SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins). SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.
Alternative Name:
Scaffold attachment factor B2, SAF-B2, SAFB2, KIAA0138
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SAFB2 polyclonal antibody detects endogenous levels of SAFB2 protein.
Immunogen:
Recombinant protein of human SAFB2.
MW: ~ 107 kDa
Swis Prot.: Q14151
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins). SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.
Alternative Name:
Scaffold attachment factor B2, SAF-B2, SAFB2, KIAA0138
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SAFB2 polyclonal antibody detects endogenous levels of SAFB2 protein.
Immunogen:
Recombinant protein of human SAFB2.
MW: ~ 107 kDa
Swis Prot.: Q14151
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review