Eps15 (phospho Tyr849) polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP67401
Catalog Number: AC-AP73674
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta- 1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Other Names:
EPS15; AF1P; Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p
Antigen Type: synthetic peptide
Antigen Type: EPS15
Gene ID: 2060
Primary Accession: P42566
Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta- 1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Other Names:
EPS15; AF1P; Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p
Antigen Type: synthetic peptide
Antigen Type: EPS15
Gene ID: 2060
Primary Accession: P42566
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