Sarcoglycan-β polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71902
Background:
Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Alternative Name:
Beta-sarcoglycan, β-sarcoglycan, Beta-SG, SG-β, SGβ, 43 kDa dystrophin-associated glycoprotein, 43DAG, A3b, SGCB
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
Specificity: Sarcoglycan-β polyclonal antibody detects endogenous levels of Sarcoglycan-β protein.
Immunogen:
Recombinant protein of human SGCB.
MW: 45kDa
Swis Prot.: Q16585
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Alternative Name:
Beta-sarcoglycan, β-sarcoglycan, Beta-SG, SG-β, SGβ, 43 kDa dystrophin-associated glycoprotein, 43DAG, A3b, SGCB
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
Specificity: Sarcoglycan-β polyclonal antibody detects endogenous levels of Sarcoglycan-β protein.
Immunogen:
Recombinant protein of human SGCB.
MW: 45kDa
Swis Prot.: Q16585
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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