SARS-CoV-2 ORF3a Peptide (LEAPFLYLYALVYFL)
€330.00
In stock
SKU
AC-VGP1138
Coronavirus Peptide
Background:
SARS-CoV-2 infection induces a storm of cytokines in later stages of progression. The viral protein ORF3a activates the NLRP3 inflammasome via promotion of TNF receptor-associated factor 3 (TRAF3)-mediated ubiquitination of apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC). ORF3a protein activates pro-IL-1β gene transcription and protein maturation, two signal essential to activation of the NLRP3 inflammasome.
Other Names: ORF3a protein, Accessory protein 3a, Protein 3a, Protein U274, Protein X1
Primary Accession: P0DTC3
Other Accession:
Gene Name: 3a
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Background:
SARS-CoV-2 infection induces a storm of cytokines in later stages of progression. The viral protein ORF3a activates the NLRP3 inflammasome via promotion of TNF receptor-associated factor 3 (TRAF3)-mediated ubiquitination of apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC). ORF3a protein activates pro-IL-1β gene transcription and protein maturation, two signal essential to activation of the NLRP3 inflammasome.
Other Names: ORF3a protein, Accessory protein 3a, Protein 3a, Protein U274, Protein X1
Primary Accession: P0DTC3
Other Accession:
Gene Name: 3a
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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