SCAP Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP8568c
Background:
SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Other Names:
Sterol regulatory element-binding protein cleavage-activating protein, SCAP, SREBP cleavage-activating protein, SCAP, KIAA0199
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8568c was selected from the Center region of human SCAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SCAP {ECO:0000303|PubMed:10570913, ECO:0000312|HGNC:HGNC:30634}
Gene ID: 22937
Primary Accession: Q12770
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Other Names:
Sterol regulatory element-binding protein cleavage-activating protein, SCAP, SREBP cleavage-activating protein, SCAP, KIAA0199
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8568c was selected from the Center region of human SCAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SCAP {ECO:0000303|PubMed:10570913, ECO:0000312|HGNC:HGNC:30634}
Gene ID: 22937
Primary Accession: Q12770
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review