SCD polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60618
Background:
Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters. SCD plays a major role in the triacylglycerol and phospholipid secretion process and in mechanisms of cellular cholesterol homeostasis. It is subject to rapid turnover in the cell and, as such, represents a model for studying selective degradation of short-lived proteins of the ER. SCD is also an important regulator of membrane fluidity. An increase in expression levels of SCD is observed in cells which are induced to differentiate into adipocytes and in certain tumor cell lines. Due to gene duplication events, the number of genes in the SCD family differs between species. Their expression patterns are affected by the level of unsaturated fatty acids in the diet of the animal.
Alternative Name:
Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase, SCD
Application Dilution: WB: 1:500~1:1000
Specificity: SCD polyclonal antibody detects endogenous levels of SCD protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SCD
MW: ~ 42 kDa
Swis Prot.: O00767
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters. SCD plays a major role in the triacylglycerol and phospholipid secretion process and in mechanisms of cellular cholesterol homeostasis. It is subject to rapid turnover in the cell and, as such, represents a model for studying selective degradation of short-lived proteins of the ER. SCD is also an important regulator of membrane fluidity. An increase in expression levels of SCD is observed in cells which are induced to differentiate into adipocytes and in certain tumor cell lines. Due to gene duplication events, the number of genes in the SCD family differs between species. Their expression patterns are affected by the level of unsaturated fatty acids in the diet of the animal.
Alternative Name:
Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase, SCD
Application Dilution: WB: 1:500~1:1000
Specificity: SCD polyclonal antibody detects endogenous levels of SCD protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SCD
MW: ~ 42 kDa
Swis Prot.: O00767
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review