Cleaved-Notch 4 (V1432) polyclonal, anti-human, primate
€470.00
In stock
SKU
AC-AP63146
Background:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Other Names:
NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4
Antigen Type: synthetic peptide
Antigen Type: NOTCH4 (HGNC:7884)
Gene ID: 4855
Primary Accession: Q99466
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Other Names:
NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4
Antigen Type: synthetic peptide
Antigen Type: NOTCH4 (HGNC:7884)
Gene ID: 4855
Primary Accession: Q99466
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