SCN4B polyclonal, anti-human, mouse, rat

Background:
Scn4b is a genetic modifier of conduction disease in mice. Differences in Scn4b mRNA and protein expression underlie this effect. Differences in Scn4b mRNA expression are caused by variants within the Scn4b locus itself (ciseQTL). Differences in Scn4b expression affect cardiac conduction by modulating Na+ current amplitude.

Alternative Name:
Sodium channel subunit beta-4, SCN4B

Application Dilution: WB: 1:500~1:1000

Specificity: SCN4B polyclonal antibody detects endogenous levels of SCN4B protein.

Immunogen:
Synthetic peptide, corresponding Human SCN4B.

MW: ~ 24 kDa

Swis Prot.: Q8IWT1

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.