SDF-1-beta human active recombinant protein
€295.00
In stock
SKU
600230
Protein Family: Cytokines
Pathway and Disease: Development and behavior, Immune System, Signaling Molecules and Interaction
Alternate Names: Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Pre-B cell growth stimulating factor, PBSF, Intercrine reduced in hepatomas, IRH, hIRH, SDF-1-beta(3-72), SDF-1-alpha(3-67), CXCL12, SDF1, SDF1A, SDF1BDescription:
Stromal Derived Growth Factor-1-beta (SDF-1-beta) is an important chemoattractant for T-lymphocytes and monocytes, but does not activate neutrophils. It activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. The human amino acid sequence shares 100% homology to the feline SDF-1-beta. Recombinant H-SDF-1-beta is a polypeptide chain comprised of 72 amino acids with a MW of 8,526 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
H-SDF-1-beta is fully biologically active when compared to standard. Activity is determined by the ability to chemoattract human peripheral T cells stimulated with IL-2 and PHA in a concentration range from 10-75 ng/ml.
Accession No.: P48061
MW: 8526 Da
Sequence:
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
Purity:
Purity Approximately 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Development and behavior, Immune System, Signaling Molecules and Interaction
Alternate Names: Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Pre-B cell growth stimulating factor, PBSF, Intercrine reduced in hepatomas, IRH, hIRH, SDF-1-beta(3-72), SDF-1-alpha(3-67), CXCL12, SDF1, SDF1A, SDF1BDescription:
Stromal Derived Growth Factor-1-beta (SDF-1-beta) is an important chemoattractant for T-lymphocytes and monocytes, but does not activate neutrophils. It activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. The human amino acid sequence shares 100% homology to the feline SDF-1-beta. Recombinant H-SDF-1-beta is a polypeptide chain comprised of 72 amino acids with a MW of 8,526 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
H-SDF-1-beta is fully biologically active when compared to standard. Activity is determined by the ability to chemoattract human peripheral T cells stimulated with IL-2 and PHA in a concentration range from 10-75 ng/ml.
Accession No.: P48061
MW: 8526 Da
Sequence:
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
Purity:
Purity Approximately 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
| Is Featured? | No |
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