SDF-1 beta mouse active recombinant protein

SDF-1 beta mouse active recombinant protein

€295.00
In stock
SKU
600369
Catalog Number: 600369
Size: 0.01 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Development and behavior, Immune System, Signaling Molecules and Interaction

Alternate Names: Stromal cell-derived factor 1, SDF-1, C-X-C motif chemokine 12, Pre-B cell growth stimulating factor, PBSF, Intercrine reduced in hepatomas, IRH, SDF-1-beta(3-72), SDF-1-alpha(3-67), CXCL12, SDF1, SDF1BDescription:
Stromal Derived Growth Factor-1beta (SDF-1beta), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1beta signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1beta shares 100% identity to feline SDF-1beta. Mouse SDF-1 beta is produced in E.coli. Recombinant mouse SDF-1beta is a non-glycosylated protein, containing 72 amino acids, with a molecular weight of 8.5 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity is determined by the ability to chemoattract human T cells at 10-75 ng/mL. Specific activity: 2 x 10e4 units/mg

Accession No.: P40224

MW: 8500 Da

Sequence:
KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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