SEC61B polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60210
Background:
The Sec61 complex forms the core element of the protein translation complex in the rough endoplasmic reticulum membrane. The complex also associates with two ubiquitous ER membrane proteins: Sec62 (also designated human translocation protein 1 or HTP1) and Sec63. The complex forms a two-way channel that transports proteins both into the ER and back to the cytosol for degradation. Specifically, it appears the b subunit facilitates the escort of proteins back to the cytoplasm for degradation by the proteasome or by other proteolytic systems.
Alternative Name:
Protein transport protein Sec61 subunit beta, SEC61B
Application Dilution: WB: 1:500~1:1000
Specificity: SEC61B polyclonal antibody detects endogenous levels of SEC61B protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SEC61B.
MW: ~ 10 kDa
Swis Prot.: P60468
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Sec61 complex forms the core element of the protein translation complex in the rough endoplasmic reticulum membrane. The complex also associates with two ubiquitous ER membrane proteins: Sec62 (also designated human translocation protein 1 or HTP1) and Sec63. The complex forms a two-way channel that transports proteins both into the ER and back to the cytosol for degradation. Specifically, it appears the b subunit facilitates the escort of proteins back to the cytoplasm for degradation by the proteasome or by other proteolytic systems.
Alternative Name:
Protein transport protein Sec61 subunit beta, SEC61B
Application Dilution: WB: 1:500~1:1000
Specificity: SEC61B polyclonal antibody detects endogenous levels of SEC61B protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SEC61B.
MW: ~ 10 kDa
Swis Prot.: P60468
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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