SEC63 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP13128a
Background:
The Sec61 complex is the central component of the proteintranslocation apparatus of the endoplasmic reticulum (ER) membrane.The protein encoded by this gene and SEC62 protein are found to beassociated with ribosome-free SEC61 complex. It is speculated thatSec61-Sec62-Sec63 may perform post-translational proteintranslocation into the ER. The Sec61-Sec62-Sec63 complex might alsoperform the backward transport of ER proteins that are subject tothe ubiquitin-proteasome-dependent degradation pathway. The encodedprotein is an integral membrane protein located in the rough ER.
Other Names:
Translocation protein SEC63 homolog, SEC63, SEC63L
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13128a was selected from the N-term region of SEC63. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SEC63 {ECO:0000303|PubMed:28375157, ECO:0000312|HGNC:HGNC:21082}
Gene ID: 11231
Primary Accession: Q9UGP8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The Sec61 complex is the central component of the proteintranslocation apparatus of the endoplasmic reticulum (ER) membrane.The protein encoded by this gene and SEC62 protein are found to beassociated with ribosome-free SEC61 complex. It is speculated thatSec61-Sec62-Sec63 may perform post-translational proteintranslocation into the ER. The Sec61-Sec62-Sec63 complex might alsoperform the backward transport of ER proteins that are subject tothe ubiquitin-proteasome-dependent degradation pathway. The encodedprotein is an integral membrane protein located in the rough ER.
Other Names:
Translocation protein SEC63 homolog, SEC63, SEC63L
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13128a was selected from the N-term region of SEC63. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SEC63 {ECO:0000303|PubMed:28375157, ECO:0000312|HGNC:HGNC:21082}
Gene ID: 11231
Primary Accession: Q9UGP8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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