Chicken IL-8/CXCL8 Elisa Kit
€0.00
In stock
SKU
SEKCN-0096
Catalog Number: SEKCN-0096
Detection Range: 15-1000 pg/ml
Sensitivity: 2 pg/ml
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Detection Range: 15-1000 pg/ml
Sensitivity: 2 pg/ml
Request Manual
Questions? Contact us!
Background:
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Long Name: Interleukin 8
Synonyms:
CXCL8, Chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine ligand 8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, IL8, Interleukin-8
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 2-2.5h
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Long Name: Interleukin 8
Synonyms:
CXCL8, Chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine ligand 8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, IL8, Interleukin-8
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 2-2.5h
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