Human FGF-19 Elisa Kit

Human FGF-19 Elisa Kit

€0.00
In stock
SKU
SEKH-0175
Catalog Number: SEKH-0175
Detection Range: 15.6-1,000 pg/ml
Sensitivity: 8 pg/ml
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Background:
FGF-19 (Fibroblast Growth Factor-19) is a secreted heparin-binding protein in the endocrine subfamily of FGFs that also includes FGF-21 and FGF-23. It is produced by epithelial cells of the ileal intestine in response to bile acids and signals through a receptor complex of FGF R4 and Klotho-beta in the liver. FGF-19 suppresses bile acid synthesis and enhances hepatic protein and glycogen synthesis. Dysregulalted FGF-19 activity is associated with the development of hypercholesterolemia, gall stones, bile acid induced diarrhoea (BAD), hepatocellular cancer, colon cancer, and metabolic syndrome.

Long Name: Fibroblast Growth Factor 19

Synonyms:
FGF19, FGF-19, Fibroblast growth factor 19

Sample Type:
Serum, Plasma, Cell culture supernatant.

Assay Lenght: 3.5h
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