Human Granzyme A Elisa Kit
€0.00
In stock
SKU
SEKH-0195
Catalog Number: SEKH-0195
Detection Range: 31.2-2,000 pg/ml
Sensitivity: 15 pg/ml
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Detection Range: 31.2-2,000 pg/ml
Sensitivity: 15 pg/ml
Request Manual
Questions? Contact us!
Background:
Granzyme A is a member of the granzyme family of the serine proteases found specifically in the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A is the most abundant protease in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262). The purified recombinant human Granzyme A consists of residues 26 to 262. After being activated by lysyl endopeptidase, it cleaves a thioester substrate.
Long Name: Granzyme A
Synonyms:
CTLA3, HFSP, HF, H factor, Granzyme 1, Fragmentin-1, Hanukkah factor,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
Granzyme A is a member of the granzyme family of the serine proteases found specifically in the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A is the most abundant protease in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262). The purified recombinant human Granzyme A consists of residues 26 to 262. After being activated by lysyl endopeptidase, it cleaves a thioester substrate.
Long Name: Granzyme A
Synonyms:
CTLA3, HFSP, HF, H factor, Granzyme 1, Fragmentin-1, Hanukkah factor,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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