Human MICB Elisa Kit
€0.00
In stock
SKU
SEKH-0242
Catalog Number: SEKH-0242
Detection Range: 156-10,000 pg/ml
Sensitivity: 80 pg/ml
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Detection Range: 156-10,000 pg/ml
Sensitivity: 80 pg/ml
Request Manual
Questions? Contact us!
Background:
MHC class I chain-related genes MICA and MICB are transmembrane glycoproteins that function as ligands for human NKG2D. The two proteins are highly related, sharing 85% amino acid identity, but are also polymorphic. Recognition of MICA or MICB by NKG2D results in the activation of NK cell cytolytic activity and/or cytokine production. MICA/B are minimally expressed on normal cells, but are frequently expressed on or shed from epithelial tumors and can be induced by bacterial and viral infections. MICA and MICB recognition is involved in tumor surveillance, viral infections, and autoimmune diseases.
Long Name: MHC Class I-related Protein B
Synonyms:
MICB, MIC-B, PERB11.2
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
MHC class I chain-related genes MICA and MICB are transmembrane glycoproteins that function as ligands for human NKG2D. The two proteins are highly related, sharing 85% amino acid identity, but are also polymorphic. Recognition of MICA or MICB by NKG2D results in the activation of NK cell cytolytic activity and/or cytokine production. MICA/B are minimally expressed on normal cells, but are frequently expressed on or shed from epithelial tumors and can be induced by bacterial and viral infections. MICA and MICB recognition is involved in tumor surveillance, viral infections, and autoimmune diseases.
Long Name: MHC Class I-related Protein B
Synonyms:
MICB, MIC-B, PERB11.2
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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