Human MIS/AMH Elisa Kit
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In stock
SKU
SEKH-0252
Catalog Number: SEKH-0252
Detection Range: 78-5,000 pg/ml
Sensitivity: 40 pg/ml
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Detection Range: 78-5,000 pg/ml
Sensitivity: 40 pg/ml
Request Manual
Questions? Contact us!
Background:
Mullerian inhibiting substance (MIS), also named anti-M?llerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.
Long Name: Mullerian-inhibiting Substance/Anti-Mullerian Hormone
Synonyms:
AMH, MIF, MIS, Muellerian hormone,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
Mullerian inhibiting substance (MIS), also named anti-M?llerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.
Long Name: Mullerian-inhibiting Substance/Anti-Mullerian Hormone
Synonyms:
AMH, MIF, MIS, Muellerian hormone,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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