Human TrkB/NTRK2 Elisa Kit
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In stock
SKU
SEKH-0333
Catalog Number: SEKH-0333
Detection Range: 6.25-400 pg/ml
Sensitivity: 3pg/ml
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Detection Range: 6.25-400 pg/ml
Sensitivity: 3pg/ml
Request Manual
Questions? Contact us!
Background:
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
Long Name: Tropomyosin receptor kinase B
Synonyms:
NTRK2, GP145-TrkB, TRKB, trk-B, Neurotrophic receptor tyrosine kinase 2, OBHD, EIEE58
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
Long Name: Tropomyosin receptor kinase B
Synonyms:
NTRK2, GP145-TrkB, TRKB, trk-B, Neurotrophic receptor tyrosine kinase 2, OBHD, EIEE58
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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