Mouse IL-1Ra Elisa Kit

Background:
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.

Long Name: Interleukin 1 Receptor Antagonist

Synonyms:
DIRA, ICIL-1RA, IL1F3, IL-1F3, IL1ra, IL-1ra, IL-1ra3, IL1RN, IL-1RN, IRAP, MVCD4

Sample Type:
Serum, Plasma, Cell culture supernatant.

Assay Lenght: 3.5h