Mouse IL-33R/ST2 Elisa Kit
€0.00
In stock
SKU
SEKM-0029
Catalog Number: SEKM-0029
Detection Range: 0.3-20 ng/ml
Sensitivity: 0.2 ng/ml
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Detection Range: 0.3-20 ng/ml
Sensitivity: 0.2 ng/ml
Request Manual
Questions? Contact us!
Background:
ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.
Long Name: Interleukin 33 Receptor
Synonyms:
DER4, Fit-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33R, Ly84, ST2, ST2L, ST2V, suppression of tumorigenicity 2, T1
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.
Long Name: Interleukin 33 Receptor
Synonyms:
DER4, Fit-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33R, Ly84, ST2, ST2L, ST2V, suppression of tumorigenicity 2, T1
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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