Mouse CXCL12 Elisa Kit

Background:
CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.

Long Name: Chemokine (C-X-C motif) ligand 12

Synonyms:
CXCL12, hIRH, hSDF-1, IRH, PBSF, PBSFSDF-1a, SCYB12, SDF1, SDF-1, SDF1A, SDF1B, SDF1SDF-1b, Stromal cell-derived factor 1, TLSF, TLSF-a, TLSF-b, TPAR1

Sample Type:
Serum, Plasma, Cell culture supernatant.

Assay Lenght: 3.5h