Mouse gP130 Elisa Kit

Background:
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

Long Name: Glycoprotein 130

Synonyms:
IL6ST, CD130, CDW130, GP130, IL-6RB, interleukin 6 signal transducer,

Sample Type:
Serum, Plasma, Cell culture supernatant.

Assay Lenght: 3.5h