Mouse OPG Elisa Kit
€0.00
In stock
SKU
SEKM-0121
Catalog Number: SEKM-0121
Detection Range: 62.5-4,000 pg/ml
Sensitivity: 30 pg/ml
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Detection Range: 62.5-4,000 pg/ml
Sensitivity: 30 pg/ml
Request Manual
Questions? Contact us!
Background:
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
Long Name: Osteoprotegerin
Synonyms:
TNFRSF11B, TNFRSF11-B, OCIF, OPG, PDB5, TR1, Tumor Necrosis Factor Receptor Superfamily Member 11b, Osteoclastogenesis Inhibitory Factor, TNF receptor superfamily member 11b,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.
Long Name: Osteoprotegerin
Synonyms:
TNFRSF11B, TNFRSF11-B, OCIF, OPG, PDB5, TR1, Tumor Necrosis Factor Receptor Superfamily Member 11b, Osteoclastogenesis Inhibitory Factor, TNF receptor superfamily member 11b,
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 3.5h
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