Sheep FGF basic Elisa Kit
€0.00
In stock
SKU
SEKS-0331
Catalog Number: SEKS-0331
Detection Range: 15-1000 pg/ml
Sensitivity: 3 pg/ml
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Detection Range: 15-1000 pg/ml
Sensitivity: 3 pg/ml
Request Manual
Questions? Contact us!
Background:
FGF basic (FGF-2) is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic binds to FGF R1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGF R1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.
Long Name: Fibroblast Growth Factor basic
Synonyms:
Basic fibroblast growth factor, bFGF, FGF basic, FGF2, FGF-2, FGF2AS, FGFB prostatropin, Fibroblast growth factor 2 (basic), GFG1, HBGF-2, HBGH-2, Heparin-binding growth factor 2, NUDT6, Prostatropin
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 2-2.5h
FGF basic (FGF-2) is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic binds to FGF R1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGF R1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.
Long Name: Fibroblast Growth Factor basic
Synonyms:
Basic fibroblast growth factor, bFGF, FGF basic, FGF2, FGF-2, FGF2AS, FGFB prostatropin, Fibroblast growth factor 2 (basic), GFG1, HBGF-2, HBGH-2, Heparin-binding growth factor 2, NUDT6, Prostatropin
Sample Type:
Serum, Plasma, Cell culture supernatant.
Assay Lenght: 2-2.5h
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