SELS Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9171c
Background:
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
Other Names:
Selenoprotein S, SelS, VCP-interacting membrane protein, VIMP, SELS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9171c was selected from the Center region of human SELS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SELENOS {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:30396}
Gene ID: 55829
Primary Accession: Q9BQE4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
Other Names:
Selenoprotein S, SelS, VCP-interacting membrane protein, VIMP, SELS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9171c was selected from the Center region of human SELS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SELENOS {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:30396}
Gene ID: 55829
Primary Accession: Q9BQE4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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