SEMA3A Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP7760c
Background:
SEMA3A is a member of the semaphorin family with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Other Names:
Semaphorin-3A, Semaphorin III, Sema III, SEMA3A, SEMAD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7760c was selected from the Center region of human SEMA3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SEMA3A
Gene ID: 10371
Primary Accession: Q14563
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SEMA3A is a member of the semaphorin family with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
Other Names:
Semaphorin-3A, Semaphorin III, Sema III, SEMA3A, SEMAD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7760c was selected from the Center region of human SEMA3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SEMA3A
Gene ID: 10371
Primary Accession: Q14563
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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