SEMA6D Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16895a
Background:
Semaphorins are a large family, including both secretedand membrane associated proteins, many of which have beenimplicated as inhibitors or chemorepellents in axon pathfinding,fasciculation and branching, and target selection. All semaphorinspossess a semaphorin (Sema) domain and a PSI domain (found inplexins, semaphorins and integrins) in the N-terminal extracellularportion. Additional sequence motifs C-terminal to the semaphorindomain allow classification into distinct subfamilies. Resultsdemonstrate that transmembrane semaphorins, like the secreted ones,can act as repulsive axon guidance cues. This gene encodes a class6 vertebrate transmembrane semaphorin that demonstrates alternativesplicing. Several transcript variants have been identified andexpression of the distinct encoded isoforms is thought to beregulated in a tissue- and development-dependent manner. [providedby RefSeq].
Other Names:
Semaphorin-6D, SEMA6D, KIAA1479
Gene Name: SEMA6D (HGNC:16770)
Gene ID: 80031
Primary Accession: Q8NFY4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Semaphorins are a large family, including both secretedand membrane associated proteins, many of which have beenimplicated as inhibitors or chemorepellents in axon pathfinding,fasciculation and branching, and target selection. All semaphorinspossess a semaphorin (Sema) domain and a PSI domain (found inplexins, semaphorins and integrins) in the N-terminal extracellularportion. Additional sequence motifs C-terminal to the semaphorindomain allow classification into distinct subfamilies. Resultsdemonstrate that transmembrane semaphorins, like the secreted ones,can act as repulsive axon guidance cues. This gene encodes a class6 vertebrate transmembrane semaphorin that demonstrates alternativesplicing. Several transcript variants have been identified andexpression of the distinct encoded isoforms is thought to beregulated in a tissue- and development-dependent manner. [providedby RefSeq].
Other Names:
Semaphorin-6D, SEMA6D, KIAA1479
Gene Name: SEMA6D (HGNC:16770)
Gene ID: 80031
Primary Accession: Q8NFY4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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