SENP2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1232a
Background:
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
Other Names:
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1232a was selected from the N-term region of human SENP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SENP2 {ECO:0000303|PubMed:10718198, ECO:0000312|HGNC:HGNC:23116}
Gene ID: 59343
Primary Accession: Q9HC62
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
Other Names:
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1232a was selected from the N-term region of human SENP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SENP2 {ECO:0000303|PubMed:10718198, ECO:0000312|HGNC:HGNC:23116}
Gene ID: 59343
Primary Accession: Q9HC62
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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