SENP6 (SUSP1) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP1152a
Background:
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1), are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin.1,2 However, covalent attachment of UBLs does not result in degradation of the modified proteins.. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases such as SUMO1-specific protease 1 (SUSP1) prior to their conjugation to target proteins.
Other Names:
Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1152a was selected from the N-term region of human SUSP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SENP6
Gene ID: 26054
Primary Accession: Q9GZR1
Other Accession: NP_056386
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1), are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin.1,2 However, covalent attachment of UBLs does not result in degradation of the modified proteins.. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases such as SUMO1-specific protease 1 (SUSP1) prior to their conjugation to target proteins.
Other Names:
Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1152a was selected from the N-term region of human SUSP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SENP6
Gene ID: 26054
Primary Accession: Q9GZR1
Other Accession: NP_056386
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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