SEPT5 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14767a
Background:
This gene is a member of the septin gene family ofnucleotide binding proteins, originally described in yeast as celldivision cycle regulatory proteins. Septins are highly conserved inyeast, Drosophila, and mouse and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ismapped to 22q11, the region frequently deleted in DiGeorge andvelocardiofacial syndromes. A translocation involving the MLL geneand this gene has also been reported in patients with acute myeloidleukemia. Alternative splicing results in multiple transcriptvariants. The presence of a non-consensus polyA signal (AACAAT) inthis gene also results in read-through transcription into thedownstream neighboring gene (GP1BB; platelet glycoprotein Ib),whereby larger, non-coding transcripts are produced. [provided byRefSeq].
Other Names:
Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1, SEPT5, PNUTL1
Gene Name: SEPTIN5 (HGNC:9164)
Gene ID: 5413
Primary Accession: Q99719
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the septin gene family ofnucleotide binding proteins, originally described in yeast as celldivision cycle regulatory proteins. Septins are highly conserved inyeast, Drosophila, and mouse and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ismapped to 22q11, the region frequently deleted in DiGeorge andvelocardiofacial syndromes. A translocation involving the MLL geneand this gene has also been reported in patients with acute myeloidleukemia. Alternative splicing results in multiple transcriptvariants. The presence of a non-consensus polyA signal (AACAAT) inthis gene also results in read-through transcription into thedownstream neighboring gene (GP1BB; platelet glycoprotein Ib),whereby larger, non-coding transcripts are produced. [provided byRefSeq].
Other Names:
Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1, SEPT5, PNUTL1
Gene Name: SEPTIN5 (HGNC:9164)
Gene ID: 5413
Primary Accession: Q99719
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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