Septin 7 (M368) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3937
Background:
The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons.
Alternative Name:
Septin-7, CDC10 protein homolog, SEPT7, CDC10
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Septin 7 (M368) polyclonal antibody detects endogenous levels of Septin 7 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 332-389 of Human Septin 7.
MW: ~ 51 kDa
Swis Prot.: Q16181
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons.
Alternative Name:
Septin-7, CDC10 protein homolog, SEPT7, CDC10
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Septin 7 (M368) polyclonal antibody detects endogenous levels of Septin 7 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 332-389 of Human Septin 7.
MW: ~ 51 kDa
Swis Prot.: Q16181
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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