Septin 8 (I203) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3938
Background:
Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1). Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm. Septin 8, Septin 4 and Septin 5 surround α-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology.
Alternative Name:
Septin-8, SEPT8, KIAA0202
Application Dilution: WB: 1:500~1:1000
Specificity: Septin 8 (I203) polyclonal antibody detects endogenous levels of Septin 8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 178-220 of Human Septin 8.
MW: ~ 55 kDa
Swis Prot.: Q92599
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1). Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm. Septin 8, Septin 4 and Septin 5 surround α-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology.
Alternative Name:
Septin-8, SEPT8, KIAA0202
Application Dilution: WB: 1:500~1:1000
Specificity: Septin 8 (I203) polyclonal antibody detects endogenous levels of Septin 8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 178-220 of Human Septin 8.
MW: ~ 55 kDa
Swis Prot.: Q92599
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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