SERPINC1 monoclonal, anti-human, rat
€0.00
In stock
SKU
AC-AM2053b
Catalog Number: AC-AM2053b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 435CT4.7.4
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 435CT4.7.4
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Other Names:
Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3
Target/Specificity:
This SERPINC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human SERPINC1.
Antigen Region:
364-393
Antigen Type: Synthetic Peptide
Gene Name: SERPINC1
Gene ID: 462
Primary Accession: P01008
NCBI Accession: NP_000479.1
Other Accession: NP_000479.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Other Names:
Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3
Target/Specificity:
This SERPINC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from human SERPINC1.
Antigen Region:
364-393
Antigen Type: Synthetic Peptide
Gene Name: SERPINC1
Gene ID: 462
Primary Accession: P01008
NCBI Accession: NP_000479.1
Other Accession: NP_000479.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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