SERPINI1 antibody (clone 1D10), anti-human
€435.00
In stock
SKU
AC-AT3828a
Catalog Number: AC-AT3828a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT3828a">Request Information
Background:
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Other Names:
Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12
Antigen Type:
Recombinant Protein
Gene Name: SERPINI1
Gene ID: 5274
NCBI Accession: NP_001116224.1;NP_005016.1
Primary Accession: Q99574
Other Accession: BC018043
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Other Names:
Neuroserpin, Peptidase inhibitor 12, PI-12, Serpin I1, SERPINI1, PI12
Antigen Type:
Recombinant Protein
Gene Name: SERPINI1
Gene ID: 5274
NCBI Accession: NP_001116224.1;NP_005016.1
Primary Accession: Q99574
Other Accession: BC018043
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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