SESN3 polyclonal, anti-human
€388.00
In stock
SKU
BS70671
Background:
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Alternative Name:
SEST3, Sestrin-3, Sestrin 3, Sestrin3,
Application Dilution: WB: 1:200 - 1:2000
Specificity: SESN3 polyclonal antibody detects endogenous levels of SESN3 protein.
Immunogen:
Recombinant protein of human SESN3.
MW: ~ 57 kDa
Swis Prot.: P58005
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Alternative Name:
SEST3, Sestrin-3, Sestrin 3, Sestrin3,
Application Dilution: WB: 1:200 - 1:2000
Specificity: SESN3 polyclonal antibody detects endogenous levels of SESN3 protein.
Immunogen:
Recombinant protein of human SESN3.
MW: ~ 57 kDa
Swis Prot.: P58005
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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