SETD3 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71071
Background:
SETD3 (SET domain containing 3) is a 594 amino acid protein that belongs to the SETD3 family. Containing one SET domain and localizing to nucleus, SETD3 is a histone methyltransferase that methylates Lys 36 of Histone H3. Overexpression of the setd3 protein in zebrafish decreases cell viability and activates caspase-3, indicating possible roles in apoptotic cell death and cell cycle regulation. In zebrafish the setd3 protein is composed of 17 α-helices and 8 β-sheets in the secondary structures.
Alternative Name:
C14orf154, Histone-lysine N-methyltransferase setd3, SET domain-containing protein 3
Application Dilution: WB: 1:500 - 1:2000, IP 1:50 - 1:100
Specificity: SETD3 polyclonal antibody detects endogenous levels of SETD3 protein.
Immunogen:
A synthetic peptide of human SETD3.
MW: ~ 67 kDa
Swis Prot.: Q86TU7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SETD3 (SET domain containing 3) is a 594 amino acid protein that belongs to the SETD3 family. Containing one SET domain and localizing to nucleus, SETD3 is a histone methyltransferase that methylates Lys 36 of Histone H3. Overexpression of the setd3 protein in zebrafish decreases cell viability and activates caspase-3, indicating possible roles in apoptotic cell death and cell cycle regulation. In zebrafish the setd3 protein is composed of 17 α-helices and 8 β-sheets in the secondary structures.
Alternative Name:
C14orf154, Histone-lysine N-methyltransferase setd3, SET domain-containing protein 3
Application Dilution: WB: 1:500 - 1:2000, IP 1:50 - 1:100
Specificity: SETD3 polyclonal antibody detects endogenous levels of SETD3 protein.
Immunogen:
A synthetic peptide of human SETD3.
MW: ~ 67 kDa
Swis Prot.: Q86TU7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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