SETX antibody (clone 2A9), anti-human, mouse, rat

Background:
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Other Names:
Probable helicase senataxin, 364-, Amyotrophic lateral sclerosis 4 protein, SEN1 homolog, SETX, ALS4, KIAA0625, SCAR1

Antigen Type:
Recombinant Protein

Gene Name: SETX {ECO:0000303|PubMed:14770181, ECO:0000312|HGNC:HGNC:445}
Gene ID: 23064
NCBI Accession: NP_055861.3
Primary Accession: Q7Z333
Other Accession: NM_015046
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .