SF3B2 antibody (clone 5D2), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3838a
Catalog Number: AC-AT3838a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IFhttps://www.abcepta.com/products/pdf_download/AT3838a-SF3B2-Antibody-monoclonal-M01">Request Information AC-AT3838a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IFhttps://www.abcepta.com/products/pdf_download/AT3838a-SF3B2-Antibody-monoclonal-M01">Request Information AC-AT3838a">Request Information
Background:
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
Other Names:
Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Antigen Type:
Recombinant Protein
Gene Name: SF3B2
Gene ID: 10992
NCBI Accession: NP_006833.2
Primary Accession: Q13435
Other Accession: NM_006842
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
Other Names:
Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Antigen Type:
Recombinant Protein
Gene Name: SF3B2
Gene ID: 10992
NCBI Accession: NP_006833.2
Primary Accession: Q13435
Other Accession: NM_006842
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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