SF3B3 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12703b
Background:
This gene encodes subunit 3 of the splicing factor 3bprotein complex. Splicing factor 3b, together with splicing factor3a and a 12S RNA unit, forms the U2 small nuclearribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3acomplex binds pre-mRNA upstream of the intron's branch site in asequence independent manner and may anchor the U2 snRNP to thepre-mRNA. Splicing factor 3b is also a component of the minorU12-type spliceosome. Subunit 3 has also been identified as acomponent of the STAGA (SPT3-TAF(II)31-GCN5L acetylase)transcription coactivator-HAT (histone acetyltransferase) complex,and the TFTC (TATA-binding-protein-free TAF(II)-containingcomplex). These complexes may function in chromatin modification,transcription, splicing, and DNA repair.
Other Names:
Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, SF3b130, STAF130, Spliceosome-associated protein 130, SAP 130, SF3B3, KIAA0017, SAP130
Gene Name: SF3B3
Gene ID: 23450
Primary Accession: Q15393
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes subunit 3 of the splicing factor 3bprotein complex. Splicing factor 3b, together with splicing factor3a and a 12S RNA unit, forms the U2 small nuclearribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3acomplex binds pre-mRNA upstream of the intron's branch site in asequence independent manner and may anchor the U2 snRNP to thepre-mRNA. Splicing factor 3b is also a component of the minorU12-type spliceosome. Subunit 3 has also been identified as acomponent of the STAGA (SPT3-TAF(II)31-GCN5L acetylase)transcription coactivator-HAT (histone acetyltransferase) complex,and the TFTC (TATA-binding-protein-free TAF(II)-containingcomplex). These complexes may function in chromatin modification,transcription, splicing, and DNA repair.
Other Names:
Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, SF3b130, STAF130, Spliceosome-associated protein 130, SAP 130, SF3B3, KIAA0017, SAP130
Gene Name: SF3B3
Gene ID: 23450
Primary Accession: Q15393
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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