SFRS15 (V641) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3953
Background:
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
Alternative Name:
Splicing factor, arginine/serine-rich 15, CTD-binding SR-like protein RA4, SR-related and CTD-associated factor 4, SCAF4, KIAA1172, SFRS15
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: SFRS15 (V641) polyclonal antibody detects endogenous levels of SFRS15 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 611-660 of Human SFRS15.
MW: ~ 126 kDa
Swis Prot.: O95104
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
Alternative Name:
Splicing factor, arginine/serine-rich 15, CTD-binding SR-like protein RA4, SR-related and CTD-associated factor 4, SCAF4, KIAA1172, SFRS15
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: SFRS15 (V641) polyclonal antibody detects endogenous levels of SFRS15 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 611-660 of Human SFRS15.
MW: ~ 126 kDa
Swis Prot.: O95104
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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