SGCE polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7541
Background:
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
dystonia 11, myoclonic, DYT11, Epsilon sarcoglycan, Epsilon SG, Epsilon-sarcoglycan, Epsilon-SG, ESG, sarcoglycan, epsilon, sgcE, SGCE_HUMAN,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: SGCE polyclonal antibody detects endogenous levels of SGCE protein.
Immunogen:
Recombinant full length Human SGCE.
MW: ~50 kDa
Swis Prot.: O43556
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
dystonia 11, myoclonic, DYT11, Epsilon sarcoglycan, Epsilon SG, Epsilon-sarcoglycan, Epsilon-SG, ESG, sarcoglycan, epsilon, sgcE, SGCE_HUMAN,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: SGCE polyclonal antibody detects endogenous levels of SGCE protein.
Immunogen:
Recombinant full length Human SGCE.
MW: ~50 kDa
Swis Prot.: O43556
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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