PFK-B polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP71868
Catalog Number: AC-AP59698
Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC, IHC
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC, IHC
Datasheet
Request Information
Background:
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).
Other Names:
PFKL; 6-phosphofructokinase; liver type; Phosphofructo-1-kinase isozyme B; PFK-B; Phosphofructokinase 1; Phosphohexokinase
Antigen Type: synthetic peptide
Antigen Type: PFKL (HGNC:8876)
Gene ID: 5211
Primary Accession: P17858
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).
Other Names:
PFKL; 6-phosphofructokinase; liver type; Phosphofructo-1-kinase isozyme B; PFK-B; Phosphofructokinase 1; Phosphohexokinase
Antigen Type: synthetic peptide
Antigen Type: PFKL (HGNC:8876)
Gene ID: 5211
Primary Accession: P17858
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