SH2D1A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6174
Background:
Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Alternative Name:
DSHP, Duncan disease SH2-protein, SAP, Signaling lymphocyte activation molecule-associated protein, SLAM-associated protein, T cell signal transduction molecule SAP,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SH2D1A polyclonal antibody detects endogenous levels of SH2D1A protein.
Immunogen:
Recombinant full length Human SH2D1A.
MW: ~ 14 kDa
Swis Prot.: O60880
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1. May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Alternative Name:
DSHP, Duncan disease SH2-protein, SAP, Signaling lymphocyte activation molecule-associated protein, SLAM-associated protein, T cell signal transduction molecule SAP,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SH2D1A polyclonal antibody detects endogenous levels of SH2D1A protein.
Immunogen:
Recombinant full length Human SH2D1A.
MW: ~ 14 kDa
Swis Prot.: O60880
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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