SHMT1 antibody (clone 4F9), anti-human
€435.00
In stock
SKU
AC-AT3884a
Catalog Number: AC-AT3884a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT3884a">Request Information
Background:
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Other Names:
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase, SHMT1
Antigen Type:
Recombinant Protein
Gene Name: SHMT1
Gene ID: 6470
NCBI Accession: NP_004160.3;NP_683718.1
Primary Accession: P34896
Other Accession: NM_004169
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Other Names:
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase, SHMT1
Antigen Type:
Recombinant Protein
Gene Name: SHMT1
Gene ID: 6470
NCBI Accession: NP_004160.3;NP_683718.1
Primary Accession: P34896
Other Accession: NM_004169
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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