SIGLEC5 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16649a
Background:
The sialic acid-binding immunoglobulin-like lectins(SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin(Ig) superfamily that mediate protein-carbohydrate interactions.They specifically interact with sialic acids in glycoproteins andglycolipids, with each SIGLEC having a particular preference forboth the nature of the sialic acid and its glycosidic linkage toadjacent sugars. SIGLECs have similar structures, includingextracellular Ig-like domains composed of an N-terminal V-setdomain followed by varying numbers of C2-set domains. It appearsthat all SIGLECs have an unusual arrangement of conserved cysteineresidues in the V-set and adjacent C2-set domains. Most SIGLECs areexpressed uniquely within the hematopoietic system (Cornish et al.,1998 [PubMed 9731071]).
Other Names:
Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC5, CD33L2, OBBP2
Gene Name: SIGLEC5
Gene ID: 8778
Primary Accession: O15389
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The sialic acid-binding immunoglobulin-like lectins(SIGLECs), such as SIGLEC5, are a subgroup of the immunoglobulin(Ig) superfamily that mediate protein-carbohydrate interactions.They specifically interact with sialic acids in glycoproteins andglycolipids, with each SIGLEC having a particular preference forboth the nature of the sialic acid and its glycosidic linkage toadjacent sugars. SIGLECs have similar structures, includingextracellular Ig-like domains composed of an N-terminal V-setdomain followed by varying numbers of C2-set domains. It appearsthat all SIGLECs have an unusual arrangement of conserved cysteineresidues in the V-set and adjacent C2-set domains. Most SIGLECs areexpressed uniquely within the hematopoietic system (Cornish et al.,1998 [PubMed 9731071]).
Other Names:
Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC5, CD33L2, OBBP2
Gene Name: SIGLEC5
Gene ID: 8778
Primary Accession: O15389
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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