SIK2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71160
Background:
QIK (Qin-induced kinase) is a serine/threonine-protein kinase that belongs to the AMPK/SNF1 kinase family. Also designated SIK2 (SNF1-like kinase 2), QIK is one of twelve human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK) related to AMPK. QIK is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. In vitro kinase tests demonstrate that QIK is capable of autophosphorylation. Elevated levels of QIK transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.
Alternative Name:
QIK, SIK-2, SNF1LK2, LOH11CR1I,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SIK2 polyclonal antibody detects endogenous levels of SIK2 protein.
Immunogen:
Recombinant protein of human SIK2.
MW: ~ 104 kDa
Swis Prot.: Q9H0K1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
QIK (Qin-induced kinase) is a serine/threonine-protein kinase that belongs to the AMPK/SNF1 kinase family. Also designated SIK2 (SNF1-like kinase 2), QIK is one of twelve human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK) related to AMPK. QIK is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. In vitro kinase tests demonstrate that QIK is capable of autophosphorylation. Elevated levels of QIK transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.
Alternative Name:
QIK, SIK-2, SNF1LK2, LOH11CR1I,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SIK2 polyclonal antibody detects endogenous levels of SIK2 protein.
Immunogen:
Recombinant protein of human SIK2.
MW: ~ 104 kDa
Swis Prot.: Q9H0K1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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