SIN3B polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS5930
Background:
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Alternative Name:
Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b, KIAA0700
Application Dilution: WB: 1:500~1:1000, IF: 1:200
Specificity: SIN3B polyclonal antibody detects endogenous levels of SIN3B protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.
MW: ~ 40, 129, 133 kDa
Swis Prot.: O75182
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Alternative Name:
Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b, KIAA0700
Application Dilution: WB: 1:500~1:1000, IF: 1:200
Specificity: SIN3B polyclonal antibody detects endogenous levels of SIN3B protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 260-305 of Human SIN3B.
MW: ~ 40, 129, 133 kDa
Swis Prot.: O75182
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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