SIRT1 antibody (clone 7C2), anti-human
€435.00
In stock
SKU
AC-AT3890a
Catalog Number: AC-AT3890a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT3890a">Request Information
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Other Names:
NAD-dependent protein deacetylase sirtuin-1, hSIRT1, 351-, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1, SIRT1, SIR2L1
Antigen Type:
Recombinant Protein
Gene Name: SIRT1 {ECO:0000303|PubMed:12535671, ECO:0000312|HGNC:HGNC:14929}
Gene ID: 23411
NCBI Accession: NP_001135970.1;NP_036370.2
Primary Accession: Q96EB6
Other Accession: BC012499
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Other Names:
NAD-dependent protein deacetylase sirtuin-1, hSIRT1, 351-, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1, SIRT1, SIR2L1
Antigen Type:
Recombinant Protein
Gene Name: SIRT1 {ECO:0000303|PubMed:12535671, ECO:0000312|HGNC:HGNC:14929}
Gene ID: 23411
NCBI Accession: NP_001135970.1;NP_036370.2
Primary Accession: Q96EB6
Other Accession: BC012499
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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