SIRT2 antibody (clone 4B11), anti-human
€435.00
In stock
SKU
AC-AT3891a
Catalog Number: AC-AT3891a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT3891a">Request Information
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Other Names:
NAD-dependent protein deacetylase sirtuin-2, 351-, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, SIRT2, SIR2L, SIR2L2
Antigen Type:
Recombinant Protein
Gene Name: SIRT2
Gene ID: 22933
NCBI Accession: NP_001180215.1;NP_036369.2;NP_085096.1
Primary Accession: Q8IXJ6
Other Accession: BC003012
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Other Names:
NAD-dependent protein deacetylase sirtuin-2, 351-, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, SIRT2, SIR2L, SIR2L2
Antigen Type:
Recombinant Protein
Gene Name: SIRT2
Gene ID: 22933
NCBI Accession: NP_001180215.1;NP_036369.2;NP_085096.1
Primary Accession: Q8IXJ6
Other Accession: BC003012
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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