SirT2 (clone 1D4-H11-H11), anti-human, mouse, rat

Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Synonyms: SIR2, SIR2L, SIR2L2

Cellular Location: Cell projection Chromosome Cytoplasm Midbody Myelin membrane Nucleus Perikaryon centriole centrosome cytoskeleton growth cone microtubule organizing center perinuclear region spindle

Immunogen:
Purified recombinant human SirT2 protein expressed in E.coli.

Gene Symbol: SirT2

Gene ID: 22933

Swiss prot: Q8IXJ6

Calculated MW: 43kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.